Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates

Summary: Background: Treatment of Blood Stream Infections (BSIs) with a combination of a β-lactam and an aminoglycoside antibiotic is widely used in intensive care units (ICUs) around the world. However, no studies have systematically examined how these drugs interact and potentially influence the...

Full description

Bibliographic Details
Main Authors: Nikos Fatsis-Kavalopoulos, Lex Roelofs, Dan I. Andersson
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422001633