Auxotrophic Selection Strategy for Improved Production of Coenzyme B12 in Escherichia coli

Summary: The production of coenzyme B12 using well-characterized microorganisms, such as Escherichia coli, has recently attracted considerable attention to meet growing demands of coenzyme B12 in various applications. In the present study, we designed an auxotrophic selection strategy and demonstrat...

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Bibliographic Details
Main Authors: Myung Hyun Noh, Hyun Gyu Lim, Daeyeong Moon, Sunghoon Park, Gyoo Yeol Jung
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220300742