Comparative transcriptome analysis of endemic and epidemic Kaposi's sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis.

Comparative transcriptome analysis of endemic and epidemic Kaposi's sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis.

In sub-Saharan Africa, endemic Kaposi's sarcoma (EnKS) is still prevalent despite high incidence of epidemic Kaposi's sarcoma (EpKS) resulting from the on-going HIV-1 epidemic. While KSHV is clearly the etiologic agent of KS, the mechanisms underlying KS development are not fully understoo...

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Bibliographic Details
Main Authors: Salum J Lidenge, Andrew V Kossenkov, For Yue Tso, Jayamanna Wickramasinghe, Sara R Privatt, Owen Ngalamika, John R Ngowi, Julius Mwaiselage, Paul M Lieberman, John T West, Charles Wood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008681

Internet

https://doi.org/10.1371/journal.ppat.1008681

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