A scalable unified framework of total and allele-specific counts for cis-QTL, fine-mapping, and prediction

Methods for eQTL mapping from total and allele-specific gene expression typically are too computationally heavy to apply to large scale studies. Here, the authors describe a computationally efficient method to identify eQTLs, fine-map and predict expression from total and allele-specific gene expres...

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Detaylı Bibliyografya
Asıl Yazarlar: Yanyu Liang, François Aguet, Alvaro N. Barbeira, Kristin Ardlie, Hae Kyung Im
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Nature Portfolio 2021-03-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-021-21592-8