Adamantylidene-substituted alkylphosphocholine TCAN26 is more active against Sporothrix schenckii than miltefosine

Sporotrichosis is the most frequent subcutaneous mycosis in the world and its increasing incidence has led to the search for new therapeutic options for its treatment. In this study, we demonstrated that three structural analogues of miltefosine (TCAN26, TC19, and TC70) showed inhibitory activity ag...

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Bibliographic Details
Main Authors: Luana Pereira Borba-Santos, Kelly Ishida, Theodora Calogeropoulou, Wanderley de Souza, Sonia Rozental
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2016-01-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016005001501&lng=en&tlng=en