Composition and diversity analysis of the TCR CDR3 repertoire in patients with idiopathic orbital inflammation using high-throughput sequencing

Composition and diversity analysis of the TCR CDR3 repertoire in patients with idiopathic orbital inflammation using high-throughput sequencing

Abstract Background Idiopathic orbital inflammation (IOI) is a nonspecific orbital inflammatory disease with the third highest prevalence among orbital diseases, and its pathogenesis is associated with T-cell-mediated immune responses. This study aimed to investigate the differences in T-cell recept...

Full description

Bibliographic Details
Main Authors: Yenan Fang, Bingyan Shen, Qin Dai, Qiqi Xie, Xinyu Li, Wencan Wu, Min Wang
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Ophthalmology
Subjects:
Idiopathic orbital inflammation
T-cell receptor
High-throughput sequencing
Glucocorticoid sensitivity
Online Access:https://doi.org/10.1186/s12886-023-03248-x

Internet

https://doi.org/10.1186/s12886-023-03248-x

Similar Items