Genetic diversity and structural analysis of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE) from Plasmodium falciparum

Genetic diversity and structural analysis of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE) from Plasmodium falciparum

Background & objectives: Plasmodium parasite harbours unique methylerythritol phosphate (MEP) pathway which is obligatory for the biosynthesis of isoprenoids. In malaria parasites, the isoprenoids are indispensable during hepatic, erythrocytic and gametocytic stages. Owing to the criticality of...

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Bibliographic Details
Main Authors: Kavita Kadian, Sonam Vijay, Ritu Rawal, Jagbir Singh, Anup Anvikar, Veena Pande, Arun Sharma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Journal of Vector Borne Diseases
Subjects:
4-diphosphocytidyl-2C-methyl-D-erythritol kinase (IspE) gene; genetic diversity; methylerythritol phosphate (MEP) pathway; molecular modeling; phylogenetic analysis; Plasmodium falciparum
Online Access:http://www.jvbd.org/article.asp?issn=0972-9062;year=2018;volume=55;issue=4;spage=271;epage=281;aulast=Kadian

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http://www.jvbd.org/article.asp?issn=0972-9062;year=2018;volume=55;issue=4;spage=271;epage=281;aulast=Kadian

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