Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered <i>E. coli</i>
The demand of plasmid DNA (pDNA) as a key element for gene therapy products, as well as mRNA and DNA vaccines, is increasing together with the need for more efficient production processes. An engineered <i>E. coli</i> strain lacking the phosphotransferase system and the pyruvate kinase A...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/12/1/150 |