PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis

Abstract Sepsis‐associated acute kidney injury (AKI) is a significant problem in critically ill children and adults resulting in increased morbidity and mortality. Fundamental mechanisms contributing to sepsis‐associated AKI are poorly understood. Previous research has demonstrated that peroxisome p...

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Bibliographic Details
Main Authors: Takuma Iwaki, Brock G. Bennion, Erin K. Stenson, Jared C. Lynn, Cynthia Otinga, Danijel Djukovic, Daniel Raftery, Lin Fei, Hector R. Wong, W. Conrad Liles, Stephen W. Standage
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.14078