Design of a Synthetic Long Peptide Vaccine Targeting HPV-16 and -18 Using Immunoinformatic Methods

Design of a Synthetic Long Peptide Vaccine Targeting HPV-16 and -18 Using Immunoinformatic Methods

Human papillomavirus types 16 and 18 cause the majority of cervical cancers worldwide. Despite the availability of three prophylactic vaccines based on virus-like particles (VLP) of the major capsid protein (L1), these vaccines are unable to clear an existing infection. Such infected persons experie...

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Bibliographic Details
Main Authors: Alexandru Tîrziu, Speranța Avram, Leonard Mada, Mihaela Crișan-Vida, Casiana Popovici, Dan Popovici, Cosmin Faur, Corina Duda-Seiman, Virgil Păunescu, Corina Vernic
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pharmaceutics
Subjects:
human papillomavirus
cervical cancer
therapeutic vaccine
epitopes
molecular docking
in silico
Online Access:https://www.mdpi.com/1999-4923/15/7/1798

Internet

https://www.mdpi.com/1999-4923/15/7/1798

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