Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning

Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning

ObjectiveTo investigate whether sound conditioning influences auditory system protection by activating adenylate activated kinase (AMPK), and if such adaption protects ribbon synapses from high-intensity noise exposure.Materials and methodsCBA mice (12 weeks old) were randomly divided into four grou...

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Bibliographic Details
Main Authors: Rui Zhao, Changhong Ma, Minjun Wang, Xinxin Li, Wei Liu, Lin Shi, Ning Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
noise-induced hearing loss
sound conditioning
synapses
ATP-consumption
hair cell
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2022.940788/full

Internet

https://www.frontiersin.org/articles/10.3389/fnsyn.2022.940788/full

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