METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

METTL3-mediated m6A methylation orchestrates mRNA stability and dsRNA contents to equilibrate γδ T1 and γδ T17 cells

Summary: γδ T cells make key contributions to tissue physiology and immunosurveillance through two main functionally distinct subsets, γδ T1 and γδ T17. m6A methylation plays critical roles in controlling numerous aspects of mRNA metabolism that govern mRNA turnover, gene expression, and cellular fu...

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Bibliographic Details
Main Authors: Zhiqiang Xiao, Shanshan Wang, Yixia Tian, Wenkai Lv, Hao Sheng, Mingjie Zhan, Qiongxiao Huang, Zhanpeng Zhang, Leqing Zhu, Chuyun Zhu, Hui Zhong, Qiong Wen, Zonghua Liu, Jingyi Tan, Yan Xu, Meixiang Yang, Yumei Liu, Richard A. Flavell, Quanli Yang, Guangchao Cao, Zhinan Yin
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
CP: Molecular biology
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723006952

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http://www.sciencedirect.com/science/article/pii/S2211124723006952

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