Insight into molecular and functional properties of NMNAT3 reveals new hints of NAD homeostasis within human mitochondria.

Among the enzymes involved in NAD homeostasis, nicotinamide mononucleotide adenylyltransferases (NMNAT1-3) are central to intracellular NAD formation. Although NMNAT3 is postulated to be a mitochondrial enzyme contributing to NAD-dependent organelle functioning, information on endogenous proteins is...

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Bibliographic Details
Main Authors: Roberta Felici, Andrea Lapucci, Matteo Ramazzotti, Alberto Chiarugi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3796565?pdf=render