Identification of Key Molecular Pathways and Associated Genes as Targets to Overcome Radiotherapy Resistance Using a Combination of Radiotherapy and Immunotherapy in Glioma Patients

Identification of Key Molecular Pathways and Associated Genes as Targets to Overcome Radiotherapy Resistance Using a Combination of Radiotherapy and Immunotherapy in Glioma Patients

Recent mechanistic studies have indicated that combinations of radiotherapy (RT) plus immunotherapy (via CSF-1R inhibition) can serve as a strategy to overcome RT resistance and improve the survival of glioma mice. Given the high mortality rate for glioma, including low-grade glioma (LGG) patients,...

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Bibliographic Details
Main Authors: Tianqi Zhang, Qiao Zhang, Xinwei He, Yuting Lu, Andrew Shao, Xiaoqiang Sun, Yongzhao Shao
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
tumor-associated macrophage cells
tumor microenvironment
translational research strategy
radiation therapy
immunotherapy
CSF-1R
Online Access:https://www.mdpi.com/1422-0067/25/5/3076

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https://www.mdpi.com/1422-0067/25/5/3076

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