Evaluation of zoledronate for the treatment of canine stage III osteosarcoma: A phase II study

Evaluation of zoledronate for the treatment of canine stage III osteosarcoma: A phase II study

Abstract Background Greater than 90% of dogs with appendicular osteosarcoma will develop pulmonary metastasis despite the standard of care. Available treatments have limited efficacy for stage III disease. Zoledronate, a bisphosphonate, induces apoptosis of canine osteosarcoma cells and appears to m...

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Bibliographic Details
Main Authors: Ashley A. Smith, Stephanie E.S. Lindley, Greg T. Almond, Noelle S. Bergman, Brad M. Matz, Annette N. Smith
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Veterinary Medicine and Science
Subjects:
bisphosphonate
bone
lung
zoledronic acid
Online Access:https://doi.org/10.1002/vms3.1000

Internet

https://doi.org/10.1002/vms3.1000

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