METHODOLOGICAL APPROACHES TO MYCOBACTERIUM TUBERCULOSIS GENOTYPING FOR EVOLUTIONARY AND EPIDEMIOLOGICAL RESEARCH
Abstract. Current genome evolution of Mycobacterium tuberculosis is marked by virtual absence of the lateral gene transfer leading to the clonal population of this species consisting of separate genetic families. Standard typing method of M. tuberculosis (IS6110-RFLP, spoligo- and VNTR-typing) are b...
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Format: | Article |
Language: | Russian |
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Sankt-Peterburg : NIIÈM imeni Pastera
2014-07-01
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Series: | Инфекция и иммунитет |
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Online Access: | https://www.iimmun.ru/iimm/article/view/76 |