Newborn bacille Calmette-Guérin vaccination induces robust infant interferon-γ-expressing natural killer cell responses to mycobacteria

Newborn bacille Calmette-Guérin vaccination induces robust infant interferon-γ-expressing natural killer cell responses to mycobacteria

Objectives: The bacille Calmette-Guérin (BCG) vaccine is usually administered at birth to protect against severe forms of tuberculosis in children. BCG also confers some protection against other infections, possibly mediated by innate immune training. We investigated whether newborn BCG vaccination...

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Bibliographic Details
Main Authors: Melissa Murphy, Sara Suliman, Libby Briel, Helen Veldtsman, Nondumiso Khomba, Hadn Africa, Marcia Steyn, Candice I. Snyders, Ilana C. van Rensburg, Gerhard Walzl, Novel N. Chegou, Mark Hatherill, Willem A. Hanekom, Thomas J. Scriba, Elisa Nemes
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:International Journal of Infectious Diseases
Subjects:
NK cells, Myeloid cells
BCG vaccination
Infant
Tuberculosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971223000693

Internet

http://www.sciencedirect.com/science/article/pii/S1201971223000693

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