Upregulated microRNA‐450b‐5p represses the development of acute liver failure via modulation of liver function, inflammatory response, and hepatocyte apoptosis

Upregulated microRNA‐450b‐5p represses the development of acute liver failure via modulation of liver function, inflammatory response, and hepatocyte apoptosis

Abstract Objective It has been evidenced that microRNAs (miRs) exert crucial effects on acute liver failure (ALF), while the detailed function of miR‐450b‐5p in ALF progression remained obscure. The purpose of this research was to unravel the regulatory mechanism of miR‐450b‐5p in ALF via modulating...

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Bibliographic Details
Main Authors: Jun Fang, Jing Kuang, Shuli Hu, Xiuhong Yang, Weibo Wan, Jing Li, Xuepeng Fan
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:Immunity, Inflammation and Disease
Subjects:
acute liver failure
apoptosis
inflammatory response
microRNA‐450b‐5p
Mouse Double Minute 2 protein
pathological change
Online Access:https://doi.org/10.1002/iid3.767

Internet

https://doi.org/10.1002/iid3.767

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