Cell-mediated immune responses to different formulations of a live-attenuated tetravalent dengue vaccine candidate in subjects living in dengue endemic and non-endemic regions

Cell-mediated immune responses to different formulations of a live-attenuated tetravalent dengue vaccine candidate in subjects living in dengue endemic and non-endemic regions

Three phase II randomized trials evaluated the safety/immunogenicity of two formulations of live-attenuated tetravalent dengue virus (TDEN) vaccine in dengue-endemic (Puerto Rico, Thailand) and non-endemic (US) regions (NCT00350337/NCT00370682/NCT00468858). We describe cell-mediated immune (CMI) res...

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Bibliographic Details
Main Authors: Philippe Moris, Kristen M. Bauer, Jeffrey R. Currier, Heather Friberg, Kenneth H. Eckels, Ines O. Esquilin, Robert V. Gibbons, Bruce L. Innis, Richard G. Jarman, Sriluck Simasathien, Peifang Sun, Stephen J. Thomas, Veerachai Watanaveeradej
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
live-attenuated tetravalent dengue candidate vaccine
cellular-mediated immune responses
dengue-primed and -unprimed populations
Online Access:http://dx.doi.org/10.1080/21645515.2019.1581536

Internet

http://dx.doi.org/10.1080/21645515.2019.1581536

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