Collateral responses to classical cytotoxic chemotherapies are heterogeneous and sensitivities are sparse
Abstract Chemotherapy resistance is a major obstacle to curing cancer patients. Combination drug regimens have shown promise as a method to overcome resistance; however, to date only some cancers have been cured with this method. Collateral sensitivity—the phenomenon whereby resistance to one drug i...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-03-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-09319-1 |