Grape seed proanthocyanidin extract-mediated regulation of STAT3 proteins contributes to Treg differentiation and attenuates inflammation in a murine model of obesity-associated arthritis.

Grape seed proanthocyanidin extract-mediated regulation of STAT3 proteins contributes to Treg differentiation and attenuates inflammation in a murine model of obesity-associated arthritis.

Grape seed proanthocyanidin extract (GSPE) is a natural flavonoid that exerts anti-inflammatory properties. Obesity is an inflammatory condition and inflammatory cells and their secretion of pro-inflammatory molecules contribute to the pathogenesis of obesity. Rheumatoid arthritis (RA) is a chronic...

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Bibliographic Details
Main Authors: Joo Yeon Jhun, Su-Jin Moon, Bo Young Yoon, Jae Kyung Byun, Eun Kyung Kim, Eun Ji Yang, Ji Hyeon Ju, Yeon Sik Hong, Jun Ki Min, Sung Hwan Park, Ho Youn Kim, Mi-La Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818494?pdf=render

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http://europepmc.org/articles/PMC3818494?pdf=render

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