Matrix Metalloproteases in Pancreatic Ductal Adenocarcinoma: Key Drivers of Disease Progression?

Pancreatic cancer is a dismal disorder that is histologically characterized by a dense fibrotic stroma around the tumor cells. As the extracellular matrix comprises the bulk of the stroma, matrix degrading proteases may play an important role in pancreatic cancer. It has been suggested that matrix m...

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Bibliographic Details
Main Authors: Etienne J. Slapak, JanWillem Duitman, Cansu Tekin, Maarten F. Bijlsma, C. Arnold Spek
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/4/80