Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic support to neurons. In the last few years, the impact of OL dysfunction and myelin damage has progressively recei...

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Bibliographic Details
Main Authors: Stefano Raffaele, Marta Boccazzi, Marta Fumagalli
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
oligodendrocytes
amyotrophic lateral sclerosis (ALS)
remyelination
neurodegenerative disease
regenerative medicine
oligodendrocyte precursor cells (OPCs)
Online Access:https://www.mdpi.com/2073-4409/10/3/565

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https://www.mdpi.com/2073-4409/10/3/565

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