CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research

CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research

Abstract Background Pathway enrichment analysis (PEA) is a common method for exploring functions of hundreds of genes and identifying disease-risk pathways. Moreover, different pathways exert their functions through crosstalk. However, existing PEA methods do not sufficiently integrate essential pat...

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Bibliographic Details
Main Authors: Haizhou Liu, Mengqin Yuan, Ramkrishna Mitra, Xu Zhou, Min Long, Wanyue Lei, Shunheng Zhou, Yu-e Huang, Fei Hou, Christine M. Eischen, Wei Jiang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Genome Medicine
Subjects:
Pathway enrichment analysis
Pathway crosstalk
Risk pathway
Molecular interaction
Network analysis
Online Access:https://doi.org/10.1186/s13073-022-01119-6

Internet

https://doi.org/10.1186/s13073-022-01119-6

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