CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism
Abstract Congenital hypothyroidism (CH) will cause cognitive impairment in the condition of delayed treatment. The hippocampus is one of the most affected tissues by CH, in which the functional structures of hippocampal neurons manifest deficiency due to aberrant expression of effector molecules. Th...
Main Authors: | Hui Wu, Guihai Suo, Tianci Li, Yuqin Zheng, Haiying Li, Feifei Shen, Yongjun Wang, Haidong Ni, Youjia Wu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-12-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-01270-4 |
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