A multiscale chemical-mechanical model predicts impact of morphogen spreading on tissue growth

Abstract The exact mechanism controlling cell growth remains a grand challenge in developmental biology and regenerative medicine. The Drosophila wing disc tissue serves as an ideal biological model to study mechanisms involved in growth regulation. Most existing computational models for studying ti...

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Bibliographic Details
Main Authors: Alireza Ramezani, Samuel Britton, Roya Zandi, Mark Alber, Ali Nematbakhsh, Weitao Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-023-00278-5