SLC12A5 promotes hepatocellular carcinoma growth and ferroptosis resistance by inducing ER stress and cystine transport changes

Abstract Background Hepatocellular carcinoma (HCC) has a poor prognosis and new effective treatments are needed. SLC12A5 plays important roles in multiple complex pathological states and is overexpressed in a variety of malignancies. However, the effects of SLC12A5 in HCC have not been determined. M...

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Bibliographic Details
Main Authors: Qing Tong, Wei Qin, Zheng‐Hao Li, Chun Liu, Zi‐Cheng Wang, Yuan Chu, Xun‐Di Xu
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.5605