Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells.

Directional migration of neural crest (NC) cells is essential for patterning the vertebrate embryo, including the craniofacial skeleton. Extensive filopodial protrusions in NC cells are thought to sense chemo-attractive/repulsive signals that provide directionality. To test this hypothesis, we gener...

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Bibliographic Details
Main Authors: Elena F Boer, Elizabeth D Howell, Thomas F Schilling, Cicely A Jette, Rodney A Stewart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4301650?pdf=render