Nε-Carboxymethyl-Lysine Modification of Extracellular Matrix Proteins Augments Fibroblast Activation

Nε-Carboxymethyl-Lysine Modification of Extracellular Matrix Proteins Augments Fibroblast Activation

The extracellular matrix (ECM) is a dynamic complex protein network that provides structural integrity and plays an active role in shaping fibroblast behavior both in health and disease. Despite its essential functions, the impact of age-associated post-translational modifications on ECM-driven fibr...

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Bibliographic Details
Main Authors:	Harshavardhana H. Ediga, Patrick Hester, Adithi Yepuri, Geereddy Bhanuprakash Reddy, Satish K. Madala
Format:	Article
Language:	English
Published:	MDPI AG 2023-10-01
Series:	International Journal of Molecular Sciences
Subjects:	advanced glycation end products Nε-carboxymethyl-lysine extracellular matrix myofibroblast transformation idiopathic pulmonary fibrosis
Online Access:	https://www.mdpi.com/1422-0067/24/21/15811

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