Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5)

Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5)

Atypical chemokine receptors (ACKRs) play pivotal roles in immune regulation by binding chemokines and regulating their spatial distribution without inducing G-protein activation. Recently, GPR182, provisionally named ACKR5, was identified as a novel ACKR expressed in microvascular and lymphatic end...

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Bibliographic Details
Main Authors: Remy Bonnavion, Shangmin Liu, Haruya Kawase, Kenneth Anthony Roquid, Stefan Offermanns
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
GPCR
ACKR
chemokine
scavenger
receptor binding
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1297596/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1297596/full

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