The β-Blocker Carvedilol Prevents Benzo(a)pyrene-Induced Lung Toxicity, Inflammation and Carcinogenesis

The β-Blocker Carvedilol Prevents Benzo(a)pyrene-Induced Lung Toxicity, Inflammation and Carcinogenesis

The current study evaluated the effects of the β-blocker carvedilol on benzo(a)pyrene (B(a)P) and its active metabolite benzo(a)pyrene diol epoxide (BPDE)-induced lung toxicity, inflammation and carcinogenesis and explored the potential mechanisms. Carvedilol blocked the BPDE-induced malignant trans...

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Bibliographic Details
Main Authors: Ayaz Shahid, Mengbing Chen, Carol Lin, Bradley T. Andresen, Cyrus Parsa, Robert Orlando, Ying Huang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
carvedilol
lung cancer
benzo(a)pyrene
β-blocker
tobacco smoking
Online Access:https://www.mdpi.com/2072-6694/15/3/583

Internet

https://www.mdpi.com/2072-6694/15/3/583

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