De novo formation of left-right asymmetry by posterior tilt of nodal cilia.
In the developing mouse embryo, leftward fluid flow on the ventral side of the node determines left-right (L-R) asymmetry. However, the mechanism by which the rotational movement of node cilia can generate a unidirectional flow remains hypothetical. Here we have addressed this question by motion and...
| Format: | Article |
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| Language: | English |
| Published: |
Public Library of Science (PLoS)
2005-08-01
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| Series: | PLoS Biology |
| Online Access: | http://dx.doi.org/10.1371/journal.pbio.0030268 |