Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice.

The interaction between fat deposition and inflammation during obesity contributes to the development of non-alcoholic fatty liver disease (NAFLD). The present study examined the effects of palmitoleate, a monounsaturated fatty acid (16:1n7), on liver metabolic and inflammatory responses, and invest...

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Main Authors: Xin Guo, Honggui Li, Hang Xu, Vera Halim, Weiyu Zhang, Huan Wang, Kuok Teong Ong, Shih-Lung Woo, Rosemary L Walzem, Douglas G Mashek, Hui Dong, Fuer Lu, Lai Wei, Yuqing Huo, Chaodong Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387145?pdf=render