The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles.

The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles.

Arenaviruses cause severe diseases in humans but establish asymptomatic, lifelong infections in rodent reservoirs. Persistently-infected rodents harbor high levels of defective interfering (DI) particles, which are thought to be important for establishing persistence and mitigating virus-induced cyt...

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Bibliographic Details
Main Authors: Christopher M Ziegler, Philip Eisenhauer, Emily A Bruce, Marion E Weir, Benjamin R King, Joseph P Klaus, Dimitry N Krementsov, David J Shirley, Bryan A Ballif, Jason Botten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4806877?pdf=render

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http://europepmc.org/articles/PMC4806877?pdf=render

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