Gallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies

Gallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies

Eight gallic acid alkyl esters (<b>1–8</b>) were synthesized via Fischer esterification and evaluated for their trypanocidal and leishmanicidal activity using bloodstream forms of <i>Trypanosoma brucei</i> and promastigotes of <i>Leishmania major</i>. The general...

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Bibliographic Details
Main Authors: Dietmar Steverding, Lázaro Gomes do Nascimento, Yunierkis Perez-Castillo, Damião Pergentino de Sousa
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
gallic acid alkyl ester
natural products
<i>Trypanosoma brucei</i>
<i>Leishmania major</i>
trypanocidal activity
leishmanicidal activity
Online Access:https://www.mdpi.com/1420-3049/27/18/5876

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https://www.mdpi.com/1420-3049/27/18/5876

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