Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners

Human and Mouse Eosinophils Differ in Their Ability to Biosynthesize Eicosanoids, Docosanoids, the Endocannabinoid 2-Arachidonoyl-glycerol and Its Congeners

High eosinophil (EOS) counts are a key feature of eosinophilic asthma. EOS notably affect asthmatic response by generating several lipid mediators. Mice have been utilized in hopes of defining new pharmacological targets to treat asthma. However, many pinpointed targets in mice did not translate int...

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Bibliographic Details
Main Authors: Anne-Sophie Archambault, Julyanne Brassard, Émilie Bernatchez, Cyril Martin, Vincenzo Di Marzo, Michel Laviolette, Louis-Philippe Boulet, Marie-Renée Blanchet, Nicolas Flamand
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
eosinophil
eicosanoid
docosanoid
leukotriene
prostaglandins
specialized pro-resolving mediators
Online Access:https://www.mdpi.com/2073-4409/11/1/141

Internet

https://www.mdpi.com/2073-4409/11/1/141

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