In vitro and in silico validation of CA3 and FHL1 downregulation in oral cancer

In vitro and in silico validation of CA3 and FHL1 downregulation in oral cancer

Abstract Background Aberrant methylation is a frequent event in oral cancer. Methods In order to better characterize these alterations, a search for genes downregulated by aberrant methylation in oral squamous cell carcinoma (OSCC) was conducted through the mining of ORESTES dataset. Findings were f...

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Bibliographic Details
Main Authors: Cláudia Maria Pereira, Ana Carolina de Carvalho, Felipe Rodrigues da Silva, Matias Eliseo Melendez, Roberta Cardim Lessa, Valéria Cristina C. Andrade, Luiz Paulo Kowalski, André L. Vettore, André Lopes Carvalho
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cancer
Subjects:
OSCC
Gene expression
Methylation
CA3
FHL1
Online Access:http://link.springer.com/article/10.1186/s12885-018-4077-3

Internet

http://link.springer.com/article/10.1186/s12885-018-4077-3

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