Metabolic Characterization of a Novel RORα Knockout Mouse Model without Ataxia

The retinoic acid receptor-related receptor α (RORα) is a nuclear receptor that plays an important role in regulation of metabolism and the immune system. Genetic deletion of the receptor yields mice with significant cerebellar developmental issues associated with severe ataxia. Although many metabo...

Full description

Bibliographic Details
Main Authors: Cyrielle Billon, Sadichha Sitaula, Thomas P. Burris
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00141/full