Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson’s disease
Abstract Parkinson’s disease (PD), classically defined as a progressive motor disorder accompanied with dopaminergic neuron loss and presence of Lewy bodies, is the second most common neurodegenerative disease. PD also has various non-classical symptoms, including cognitive impairments. In addition,...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-10-01
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Series: | Molecular Brain |
Online Access: | http://link.springer.com/article/10.1186/s13041-019-0514-8 |