Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson’s disease

Abstract Parkinson’s disease (PD), classically defined as a progressive motor disorder accompanied with dopaminergic neuron loss and presence of Lewy bodies, is the second most common neurodegenerative disease. PD also has various non-classical symptoms, including cognitive impairments. In addition,...

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Bibliographic Details
Main Authors: Milos Stanojlovic, Jean Pierre Pallais, Michael K. Lee, Catherine M. Kotz
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Molecular Brain
Online Access:http://link.springer.com/article/10.1186/s13041-019-0514-8