Hibiscus sabdariffa synthesized gold nanoparticles ameliorate aluminum chloride induced memory deficits through inhibition of COX-2/BACE-1 mRNA expression in rats

Hibiscus sabdariffa synthesized gold nanoparticles ameliorate aluminum chloride induced memory deficits through inhibition of COX-2/BACE-1 mRNA expression in rats

Alzheimer’s disease (AD) is a major health challenge worldwide, especially among the elderly. The disease is associated with cognitive and memory deficits. This study investigated the effect of Hibiscus sabdariffa synthesized-gold nanoparticles (HS-AuNPs) on AlCl3-induced memory deficits in rats. Fo...

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Bibliographic Details
Main Authors: Scholastica O. Anadozie, Duncan O. Effiom, Olusola B. Adewale, Jodie Jude, Itumeleng Zosela, Oluwole B. Akawa, Juliet N. Olayinka, Saartjie Roux
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Arabian Journal of Chemistry
Subjects:
Aluminum chloride
Alzheimer’s disease
Cyclooxygenase-2
Hibiscus sabdariffa
Gold nanoparticle
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223000655

Internet

http://www.sciencedirect.com/science/article/pii/S1878535223000655

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