Discrimination of the chemotherapy resistance status of human leukemia and glioblastoma cell lines by MALDI-TOF-MS profiling

Abstract Chemotherapy mistreatment is partially due to a lack of rapid and reliable tools to discriminate between sensitive and resistant phenotypes. In many cases, the resistance mechanism is not fully understood, contributing to the diagnostic tools' absence. This work aims to determine the c...

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Bibliographic Details
Main Authors: Martín Ledesma, Daniela Poodts, Sofía Amoia, Silvia Hajos, Ariela Fundia, Carlos Vay, Matías Pibuel, Silvina Lompardía
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32608-2