Sex-specific effects of methylenetetrahydrofolate reductase polymorphisms on schizophrenia with methylation changes

Background: Methylenetetrahydrofolate reductase (MTHFR) is the critical enzyme in biotransformation. The polymorphism of MTHFR is a risk factor for schizophrenia. However, whether the MTHFR polymorphism is associated with schizophrenia disease phenotypes and what is the underlying mechanism of MTHFR...

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Bibliographic Details
Main Authors: Lin Wan, Guofu Zhang, Min Liu, Chuanyue Wang, Yuhong Li, Rena Li
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Comprehensive Psychiatry
Online Access:http://www.sciencedirect.com/science/article/pii/S0010440X19300446