NIR-enhanced Pt single atom/g-C3N4 nanozymes as SOD/CAT mimics to rescue ATP energy crisis by regulating oxidative phosphorylation pathway for delaying osteoarthritis progression

NIR-enhanced Pt single atom/g-C3N4 nanozymes as SOD/CAT mimics to rescue ATP energy crisis by regulating oxidative phosphorylation pathway for delaying osteoarthritis progression

Osteoarthritis (OA) progresses due to the excessive generation of reactive oxygen and nitrogen species (ROS/RNS) and abnormal ATP energy metabolism related to the oxidative phosphorylation pathway in the mitochondria. Highly active single-atom nanozymes (SAzymes) can help regulate the redox balance...

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Bibliographic Details
Main Authors: Jianhui Xiang, Xin Yang, Manli Tan, Jianfeng Guo, Yuting Ye, Jiejia Deng, Zhangrui Huang, Hanjie Wang, Wei Su, Jianwen Cheng, Li Zheng, Sijia Liu, Jingping Zhong, Jinmin Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-06-01
Series:Bioactive Materials
Subjects:
ATP energy crisis
Osteoarthritis progression
Oxidative phosphorylation pathway
Nanozymes
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2400063X

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X2400063X

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