Dimeric dipeptide mimetics of the nerve growth factor loops 3 and 4 are active in a model of ischemic stroke

Pharmacological activity of dimeric dipeptide mimetics of the nerve growth factor loops 3 and 4, correspondingly GTS-115 and GK-2, was studied in a model of ischemic stroke, induced by transient middle cerebral artery occlusion in rats. The both compounds, at i.p. subchronic administration (0,5-1 mg...

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Detalhes bibliográficos
Main Authors: P. Y. Povarnina, T. A. Gudasheva, S. B. Seredenin
Formato: Artigo
Idioma:Russian
Publicado em: LLC “Publisher OKI” 2016-09-01
Colecção:Фармакокинетика и Фармакодинамика
Assuntos:
Acesso em linha:https://www.pharmacokinetica.ru/jour/article/view/182