Validation of reference gene stability for miRNA quantification by reverse transcription quantitative PCR in the peripheral blood of patients with COVID-19 critical illness.

Validation of reference gene stability for miRNA quantification by reverse transcription quantitative PCR in the peripheral blood of patients with COVID-19 critical illness.

The COVID-19 pandemic has created an urgency to study the host gene response that leads to variable clinical presentations of the disease, particularly the critical illness response. miRNAs have been implicated in the mechanism of host immune dysregulation and thus hold potential as biomarkers and/o...

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Bibliographic Details
Main Authors: Amanda Formosa, Erica Acton, Amy Lee, Paul Turgeon, Shehla Izhar, Pamela Plant, Jim N Tsoporis, Sabri Soussi, Uriel Trahtemberg, Andrew Baker, Claudia C Dos Santos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0286871

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https://doi.org/10.1371/journal.pone.0286871

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