Trivalent SARS-CoV-2 S1 Subunit Protein Vaccination Induces Broad Humoral Responses in BALB/c Mice

This paper presents a novel approach for improving the efficacy of COVID-19 vaccines against emergent SARS-CoV-2 variants. We have evaluated the immunogenicity of unadjuvanted wild-type (WU S1-RS09cg) and variant-specific (Delta S1-RS09cg and OM S1-RS09cg) S1 subunit protein vaccines delivered eithe...

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Bibliographic Details
Main Authors: Muhammad S. Khan, Eun Kim, Shaohua Huang, Thomas W. Kenniston, Andrea Gambotto
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/11/2/314