Single Nucleotide Variants of the Human TIM-1 IgV Domain with Reduced Ability to Promote Viral Entry into Cells

Single Nucleotide Variants of the Human TIM-1 IgV Domain with Reduced Ability to Promote Viral Entry into Cells

Human T-cell immunoglobulin mucin 1 (hTIM-1) is known to promote cellular entry of enveloped viruses. Previous studies suggested that the polymorphisms of hTIM-1 affected its function. Here, we analyzed single nucleotide variants (SNVs) of hTIM-1 to determine their ability to promote cellular entry...

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Bibliographic Details
Main Authors: Takanari Hattori, Takeshi Saito, Hiroko Miyamoto, Masahiro Kajihara, Manabu Igarashi, Ayato Takada
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Viruses
Subjects:
TIM-1
polymorphism
pseudotyped virus
glycoprotein
entry
Online Access:https://www.mdpi.com/1999-4915/14/10/2124

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https://www.mdpi.com/1999-4915/14/10/2124

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