MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to drive pro-tumorigenic gene expression programs, pr...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Tessa M Popay, Jing Wang, Clare M Adams, Gregory Caleb Howard, Simona G Codreanu, Stacy D Sherrod, John A McLean, Lance R Thomas, Shelly L Lorey, Yuichi J Machida, April M Weissmiller, Christine M Eischen, Qi Liu, William P Tansey
स्वरूप: लेख
भाषा:English
प्रकाशित: eLife Sciences Publications Ltd 2021-01-01
श्रृंखला:eLife
विषय:
cancer
MYC
ribosome biogenesis
ऑनलाइन पहुंच:https://elifesciences.org/articles/60191

इंटरनेट

https://elifesciences.org/articles/60191

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