MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

The oncoprotein transcription factor MYC is a major driver of malignancy and a highly validated but challenging target for the development of anticancer therapies. Novel strategies to inhibit MYC may come from understanding the co-factors it uses to drive pro-tumorigenic gene expression programs, pr...

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Detaylı Bibliyografya
Asıl Yazarlar: Tessa M Popay, Jing Wang, Clare M Adams, Gregory Caleb Howard, Simona G Codreanu, Stacy D Sherrod, John A McLean, Lance R Thomas, Shelly L Lorey, Yuichi J Machida, April M Weissmiller, Christine M Eischen, Qi Liu, William P Tansey
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: eLife Sciences Publications Ltd 2021-01-01
Seri Bilgileri:eLife
Konular:
cancer
MYC
ribosome biogenesis
Online Erişim:https://elifesciences.org/articles/60191

Internet

https://elifesciences.org/articles/60191

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