Senescence in osteoarthritis: from mechanism to potential treatment

Abstract Osteoarthritis (OA) is an age-related cartilage degenerative disease, and chondrocyte senescence has been extensively studied in recent years. Increased numbers of senescent chondrocytes are found in OA cartilage. Selective clearance of senescent chondrocytes in a post-traumatic osteoarthri...

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Bibliographic Details
Main Authors: Yikai Liu, Zian Zhang, Tao Li, Hao Xu, Haining Zhang
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-022-02859-x